Matt Czimskey drove in 4 runs and Baylor turned three double plays as the Bears beat Missouri 10-5.
Baylor (33-24) moved to 2-0 in its pool and will play Oklahoma on Saturday, the final day of pool play.
Missouri (39-16) is 0-2 in pool play and will play Oklahoma State on Saturday. The Tigers, seeded second in the tournament, cannot win the pool and thus won't advance to the championship game on Sunday.
Missouri took a quick lead in the top of the 1st, on a 2-run double by Jacob Priday. But the Bears answered with 3 runs in the bottom of the inning, 2 on a home run over the left-field wall by Czimskey, who also homered in Baylor's tournament opener against Oklahoma State.
The Tigers went up 4-3 in the 4th on a solo home run by Evan Frey, but Baylor took the lead for good with a 5-run 5th-inning outburst against Missouri starter Aaron Crow (8-3). Beamer Weems had a run-scoring double and Czimskey added a 2-run single in the inning for the Bears.
Weems and Chase Gerdes each had 3 hits for Baylor.
Randall Linebaugh (3-5), the second of three Baylor pitchers, allowed 3 hits in 3 2-3 innings. Nick Cassavechia pitched the final 2 1-3 innings to record his 10th save.