The Oklahoma Highway Patrol worked a multiple-vehicle crash on the Will Rogers Turnpike Saturday evening.
The wreck, which included five vehicles, backed up eastbound traffic on Interstate 44 near Catoosa near mile marker 243 for about two hours.
OHP says a semi truck driver failed to slow down near a construction zone and hit four other vehicles.
Troopers say two people had to be taken to a hospital. No word on their condition.
All lanes have been reopened.