White House Coronavirus Response Coordinator Dr. Deborah Birx said the U.S. will likely be physical distancing through the summer.
The news comes as some businesses begin to reopen, while state and local officials around the country ease restrictions to get people back to work.
White House Economic Advisor Kevin Hassett said the pandemic could bring levels of unemployment not seen since the Great Depression.
Despite some uncertainty, many states across the country are now easing restrictions and allowing some businesses to reopen, including in Oklahoma.
Dr. Birx said she's been in contact with the governors of some of those states.
"They understand the risk. They talk about this not as turning on a light switch, but slowly turning up the dimmer,” said Dr. Birx.
Colorado's state-wide Stay at Home order ends Monday, but the Governor is warning that its not a return to normal.
In Alaska, restaurants can now serve dine-in customers but at just 25 percent seating capacity.
Other states like Pennsylvania and New York are hoping to reopen on a regional basis in the coming weeks.