Booker Woodfox nailed a three-pointer with 26 seconds left to push Creighton past Oral Roberts 65-64 on Saturday.
Robert Jarvis, who led ORU with 17 points, made two free throws with 35 seconds remaining to put the Golden Eagles up 64-62.
Nine seconds later, Woodfox made his third three-pointer of the game. It was Creighton's only field goal in the final 5:37.
ORU's Adam Liberty and Moses Ehambe each missed long jumpers in the last five seconds as the Bluejays (19-8) snapped a 4-game road losing streak.
The Golden Eagles (20-7) lost at home for the first time in 13 games this season.
The Associated Press contributed to this story.